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Usage
- AHCC was discovered to be as a biological response modifier (BRM) and to possess powerful antitumor properties when given at a higher dosage.
- Research has been conducted at Hokkaido University, Kyorin University, and Teikyo University; with clinical tests performed at hospitals in the U.S.A., Japan and China.
- AHCC works by boosting the immune system function including increasing macrophages.
- AHCC also increase NK cells, killer T-cells, and to induce cytokine production; creating a stronger immune response throughout the body.
- AHCC helps to induce levels of interferon-gamma, IL-2, and TNF-alpha etc.
- Effects on survival elongation of the tumor-bearing model in combined with anti-cancer agents.
- Decreasing effects on the side effects caused by anticancer agents.
- Inducing effects on drug-metabolism enzymes in liver.
- Protective effects on liver injury.
- Effects on inhibition of lipid peroxidation.
- In animal studies, it is demonstrated that AHCC prevent streptozotocin (STZ)-induced pancreatic injury in rats by oral administration. AHCC showed a significant activity to prevent rats from STZ-induced diabetes.
- AHCC suppressed several physiological and biochemical disorders such as hepatic injuries, cardiovascular disorders occurred by a long-term administration of EtOH.
- AHCC relieves the toxicity of antitumor agents fluorouracil (5-FU) and cyclophosphamide (CY).
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